We are pleased to share our new publication in Physical Chemistry Chemical Physics titled “Perlin- and Bohlmann-type effects in cyclohexylamine and 1-aminopiperidine derivatives.”
In this work, we investigate how classical stereoelectronic effects, namely the Perlin and Bohlmann effects, manifest in cyclohexylamine and 1-aminopiperidine derivatives. By analyzing spectroscopic data, we explore the electronic interactions responsible for these phenomena and their relationship with molecular conformation.
Our results indicate that the Bohlmann-type effect observed in N–H stretching vibrations is mainly associated with hyperconjugative interactions, whereas the Perlin effect observed in 1JCH coupling constants is largely driven by steric (Lewis-type) interactions, with hyperconjugation playing a secondary role in modulating the magnitude of the effect.
